{"product_id":"isotope-tracers-in-metabolic-research-principles-and-practice-of-kinetic-analysis-9780471462095","title":"Isotope Tracers in Metabolic Research: Principles and Practice of Kinetic Analysis","description":"In the past few years, the number of applications of tracers for in vivo biomedical studies has greatly increased. New analytical tools at the genetic and protein levels have spurred this growth, opening the door for a deeper understanding of metabolic events. This in turn promises to yield significant advances in the understanding and treatment of human disease. \u003cp\u003eNow fully revised and expanded, \u003ci\u003eIsotope Tracers in Metabolic Research\u003c\/i\u003e, Second Edition is the established definitive text on stable and radioactive isotope tracers. In unique, multidisciplinary fashion, it presents comprehensive coverage of new methodological, mathematical, and theoretical approaches.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eThis new Second Edition includes: \u003c\/b\u003e\u003c\/p\u003e \u003cul\u003e \u003cli\u003eAll-new chapters on nuclear magnetic resonance, mass isotopomer analysis, and methods of protein metabolism analysis\u003c\/li\u003e \u003cli\u003eA completely updated categorized list of over 750 references\u003c\/li\u003e \u003cli\u003eMajor advances in the development of mass isotopomer and positional isotopomer techniques, noninvasive isotope techniques for studying metabolic pathways, hyphenated techniques, and new tracer techniques\u003c\/li\u003e \u003cli\u003eThe latest developments in quantification of DNA synthesis and mass spectrometry spurred by genome sequencing and proteomics\u003c\/li\u003e \u003cli\u003eNew coverage of mathematical modeling\u003c\/li\u003e \u003cli\u003eExpanded coverage of microdialysis probes, laboratory procedures, and regulatory issues related to human studies\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eIn this complete guide to performing tracer studies, the authors systematically cover tracer selection, modeling considerations, sample derivitization, mass spectrometry analysis, and data interpretation. Problems and discussion questions highlight key points in each chapter. Isotope \u003ci\u003eTracers in Metabolic Research\u003c\/i\u003e, Second Edition offers students and researchers a comprehensive, practical resource for utilizing the latest tracer methodologies.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAbout the Author\u003c\/b\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eRobert R. Wolfe\u003c\/b\u003e, Ph.D. is currently John H. Sealy Distinguished Chair in Clinical Research at the University of Texas Medical Branch and Chief of Metabolism at the Shriners Burns Hospital in Galveston, Texas. He received his Ph.D. from the University of California, Santa Barbara, spent 8 years as a faculty member at Harvard Medical School, and moved to Galveston in 1983. He is widely recognized for his research in physiological metabolism using isotopically labeled tracers.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eDavid L. Chinkes\u003c\/b\u003e, Ph.D. received his Ph.D. in Mathematical Modeling in Metabolism in 1996 from the University of Texas Medical Branch, and is currently Associate Professor of Surgery and a member of the Metabolism Unit at the Shriners Burns Hospital at Galveston, Texas. His research looks at developing new methods for measuring metabolic parameters in vivo.\u003c\/p\u003e\u003cbr\u003e","brand":"Wiley-Liss","offers":[{"title":"Default Title","offer_id":50324793983250,"sku":"9780471462095","price":325.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0831\/4771\/8930\/files\/img_36dfee73-75d7-4bc5-a965-f4f791b02252.jpg?v=1727673980","url":"https:\/\/surprise-castle.myshopify.com\/products\/isotope-tracers-in-metabolic-research-principles-and-practice-of-kinetic-analysis-9780471462095","provider":"Surprise Castle","version":"1.0","type":"link"}