{"product_id":"antiinflammatory-effect-of-prednisolone-ethoniosome-marketed-products-9783659565472","title":"Antiinflammatory Effect of Prednisolone Ethoniosome\u0026 Marketed Products","description":"Ethoniosomes (EVs) composed of span 60: CH (7:3) containing 20% (v\/v) ethanol and prepared by TFH method was prepared and tested for its irritation potential to the ocular tissue and its in vivo anti-inflammatory activity compared to commercial products. Also, the duration of action of the prepared EVs was determined. In addition to, measurement of the cumulative increase in the IOP for both; the prepared EVs and the conventional formulations. The results showed that, no signs of irritation were observed for either the cornea or the conjunctiva. The ocular anti-inflammatory activity of EVs entrapping Pred A and Pred P was significantly higher compared to conventional formulations. The cumulative IOP of TFH-EVs entrapping either Pred A or Pred P showed smaller increase in IOP compared to conventional formulations. Further, an obviously prolonged absorption and relatively slower elimination rates were demonstrated for Pred A EVs, Pred P EVs formulations. In conclusion, EVs may serve as a novel delivery system improving the ultimate outcome any drug can offer; which is high efficacy in terms of activity and duration of action and a lesser side effects in terms of IOP raising potentia\u003cbr\u003e","brand":"LAP Lambert Academic Publishing","offers":[{"title":"Default Title","offer_id":50434127921426,"sku":"9783659565472","price":39.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0831\/4771\/8930\/files\/img_1056d06d-7dc0-467d-94f9-056bc5ad2eb0.jpg?v=1729593948","url":"https:\/\/surprise-castle.myshopify.com\/products\/antiinflammatory-effect-of-prednisolone-ethoniosome-marketed-products-9783659565472","provider":"Surprise Castle","version":"1.0","type":"link"}